Publication | The Okamoto group

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University of Toyama

Okamoto Group

Publication/ 原著論文

15.
Electrochemical Single-Carbon Insertion via Distonic Radical Cation Intermediates

Tatsuya Morimoto, Yoshio Nishimoto, Taku Suzuki-Osborne, Su-Gi Chong, Kazuhiro Okamoto, Tomoki Yoneda, Azusa Kikuchi, Daisuke Yokogawa, Mahito Atobe, Naoki Shida

J. Am. Chem. Soc., 2025, accepted.

Preprint version (ChemRxiv)

14.
Additive-controlled Chemoselective Inter-/Intramolecular Hydroamination via Electrochemical PCET Process

Kazuhiro Okamoto, Naoki Shida, Mahito Atobe

Beilstein J. Org. Chem., 2024, 20, 264-271.

13.
Electrosynthesis of Artificial Peptides and Nucleosides via the Nitromethane–Lithium Perchlorate Electrolyte System: A Review

Kazuhiro Okamoto and Kazuhiro Chiba*

ChemElectroChem, 2024, 11, e202300493.

12.
Electrochemical [3+2] cycloaddition proceeding at low electrolyte concentration in laminar-flow microreactor

Kazuhiro Okamoto, Naoki Shida, Mahito Atobe

ChemElectroChem, 2023, 10, e202300386.

11.
C–C Bond Cleavage at the N-α Position Enabled by the Low-potential Electrochemical Oxidation of the 2,7-Dimethoxynaphthyl Electroauxiliary

Kazuhiro Okamoto, Yasushi Imada, Naoki Shida, Yoshikazu Kitano, Mahito Atobe, Kazuhiro Chiba*

Electrochemistry, 2023, 91, 112006.

10.
Stereoselective Production of Imino-D-ribitol and C-Azanucleosides through Electrochemical C−H Functionalization

Haruka Morizumi+, Kazuhiro Okamoto+, Shinnosuke Akahane, Hitoshi Takemae, Mami Oba, Yohei Okada, Yoshikazu Kitano, Tetsuya Mizutani, Kazuhiro Chiba*(+ Equally first)

Eur. J. Org. Chem., 2023, 26, e202201046.
[Selected as VIP paper]

9.
Designing Modular Assembly of Electrochemical Flow Microreactor as an Enabling Technology of Electrosynthesis in a Laminar Flow

Ayano Yata, Yuto Nakamura, Kazuhiro Okamoto, Naoki Shida, Mahito Atobe

Eur. J. Org. Chem., 2022, e202200980.

8.
Oxidation Potential Gap (ΔEox): The Hidden Parameter in Redox Chemistry

Kazuhiro Okamoto, Naoki Shida, Haruka Morizumi, Yoshikazu Kitano, Kazuhiro Chiba

Angew. Chem. Int. Ed., 2022, 61, e202206064.

7.
Direct Anodic N-α Hydroxylation: Accessing Versatile Intermediates for Azanucleoside Derivatives

Yuma Kurose, Kazuhiro Okamoto, Yohei Okada, Yoshikazu Kitano, Kazuhiro Chiba*

Asian J. Org. Chem., 2022, 11, e202100756.

6.
Design, synthesis and biological evaluation of simplified analogues of MraY inhibitory natural product with rigid scaffold

Kazuhiro Okamoto, Aoi Ishikawa, Ryotaro Okawa, Kazuki Yamamoto, Toyotaka Sato, Shin-ichi Yokota, Kazuhiro Chiba, Satoshi Ichikawa*

Bioorg. Med. Chem., 2022, 55, 116556.

5.
Hydrosilane-Mediated Electrochemical Reduction of Amides

Kazuhiro Okamoto, Shingo Nagahara, Yasushi Imada, Risako Narita, Yoshikazu Kitano, Kazuhiro Chiba*

J. Org. Chem., 2021, 86, 15992–16000.

4.
Electrochemical Synthesis of Imino-C-Nucleosides by “Reactivity Switching” Methodology for in situ Generated Glycoside Donors

Kazuhiro Okamoto, Mizuki Tsutsui, Haruka Morizumi, Yoshikazu Kitano, Kazuhiro Chiba*

Eur. J. Org. Chem., 2021, 2479-2484

3.
Electrochemical Total Synthesis of Pyrrolophenanthridone Alkaloids: Controlling the Anodically Initiated Electron Transfer Process

Kazuhiro Okamoto and Kazuhiro Chiba*

Org. Lett., 2020, 22, 3613-3617.

2.
Liquid-Phase Synthesis of N-Functionalized Azanucleoside-Incorporated Oligonucleotides and Development of Anodic C(sp3)-H Acetoxylation Reaction for Direct Preparation of Azaribose

Kazuhiro Okamoto, Naoki Shida, Mizuki Tsutsui, Kazuhiro Chiba*

Synlett, 2019, 30, 1303-1307.

1.
Synthesis of Ribo-Azanucleosides by Anodic Oxidation: Reactivity Control of Intermediate for Efficient Access to Pharmacophores

Kazuhiro Okamoto, Takao Shoji, Mizuki Tsutsui, Naoki Shida, Kazuhiro Chiba*

Chem. Eur. J., 2018, 24, 17902-17905.

解説記事等

2.
ニトロメタン-過塩素酸リチウム系を反応場とする含窒素化合物の電解合成

岡本一央, 千葉一裕

有機合成化学協会誌, 2025, xxxx.

1.
有機電解反応を利用した生体関連分子の合成戦略

岡本一央, 北野克和, 千葉一裕

化学と生物, 2021, 59, 212-215.

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